NAT means Nucleic Acid Amplification Testing (NAT).Nucleic Acid Testing (NAT) in Blood Bank is a molecular method of screening blood donations for Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV), Hepatitis C Virus (HCV). It is a highly sensitive technology that directly detects viral DNA or RNA.
It detects the presence of virus earlier in an infection than serologic methods. It has helped in decreasing the window period of different transfusion transmitted infections & helped to reduce their transmission and thus provided an additional layer of blood safety.
At Dr. Hedgewar Blood Bank, Nagpur, we have NAT Laboratory where Nucleic Acid Testing is performed on Cobas S201 Taq Screen MPX (Roche Diagnostic, USA) and Real Time Polymerase Chain Reaction (RT-PCR) technology is used for simultaneous detection of Human Immunodeficiency Virus-1 (group M and O) RNA, Human Immunodeficiency Virus -2 RNA, Hepatitis C Virus RNA and Hepatitis B Virus DNA.